Lurie winners’ epigenetic view into the biology of aging diseases

The two recipients of this year’s Lurie Prize see the potential to address multiple diseases at once via common mechanisms of lifespan regulation, with epigenetics as a foothold.

“Epigenetics is a nexus that can integrate a lot of different stimuli. It’s also long-lasting, and can stay into the next generation, but it can also be reversed via enzymes,” which can be targeted by small molecules, said prize recipient Anne Brunet, a professor at Stanford University...