BioCentury
DATA GRAPHICS | Product Development

Lengthy TRPV1 pipeline now backed by Nobel prize

October 5, 2021 2:11 AM UTC

The now Nobel Prize-winning discovery of TRPV1 has led to a well-stocked therapeutic pipeline

The discovery that won UCSF Professor David Julius a Nobel Prize on Monday has led to a therapeutic pipeline containing at least 19 candidates and two marketed products, according to BioCentury’s BCIQ database.  

In the late 1990s, Julius identified and cloned a receptor responsible for encoding temperature sensation. The protein, called TRPV1, is involved in pain signaling and companies quickly recognized its potential for treating pain conditions...