ARTICLE | Product Development

Macrophage therapies to watch at AACR

BioCentury analyzes strategies targeting macrophages at AACR21

April 9, 2021 1:31 AM UTC

Macrophage cell therapies may make headlines this weekend as the first CAR macrophage data in an immunocompetent animal model read out at AACR, but the conference will also showcase a spate of other strategies designed to harness antitumor activity of the innate immune cells. 

As the understanding of the immune system’s role in cancer has evolved past effector T cells, macrophages have emerged as one of the newest sources of immuno-oncology targets and therapies — a trend BioCentury has been tracking at the American Association for Cancer Research (AACR) meeting since 2019. ...