What it will take to meet CEPI’s 100-day vaccine goal for the next pandemic

As CEPI looks to prepare for the next pandemic, it has set a lofty goal to reduce to 100 days the time from sequencing the pathogen to a regulatory submission of a vaccine. But meeting that mark will require invention of technologies that don’t yet exist, layered on top of step changes in almost all stages of the process from day one to 100.

It may also require a scientific shift in vaccinology away from the focus on neutralizing antibodies, towards a broader recruitment of the immune system, catching up with advances made in immunology that other fields, notably cancer, have already embraced...