BioCentury
ARTICLE | Product Development

Following fast-fail model, Quench passes on hard-to-drug inflammation target gasdermin D 

March 10, 2021 12:22 AM UTC

Atlas-incubated Quench became the latest example of the VC’s ethos of failing quickly and transparently after announcing it had auctioned off its IP for small molecule inhibitors of hard-to-drug inflammation target gasdermin D.

In a Twitter thread posted Tuesday, Quench Bio said it would wind down operations and return capital to investors because it failed to “identify a potent, selective chemical series to progress — which was our goal by Q1 2021,” despite running “a thorough discovery campaign with several approaches using multiple, orthogonal technologies.” ...

BCIQ Company Profiles

Atlas Venture

Quench Bio

BCIQ Target Profiles

Gasdermin D (GSDMD)