Two half or full shots of Moderna COVID vaccine yield similar antibody levels: Data Byte

Immunogenicity data from Moderna’s COVID-19 vaccine hint that prime-boost vaccination with half the authorized dose may provide the same level of protection as the full dose.

The data lend at least some weight to the idea of stretching supplies by administering two 50 μg shots instead of two 100 μg shots. The catch, however, is that correlates of protection have not yet been established for COVID-19 vaccines, which means decision-makers are still largely groping in the dark...