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The first COVID-19 vaccine data in the elderly may bode well for the next candidates: Data Byte

A comparison of neutralization titers and protection data across candidates and age groups

November 20, 2020 2:34 AM UTC
Updated on Nov 20, 2020 at 3:03 AM UTC

A pressing question about COVID-19 vaccines is how well they will perform in the elderly, who are at higher risk for severe disease. Wednesday’s report of strong efficacy in subjects over 65 given Pfizer and BioNTech’s mRNA vaccine could portend good news for several of the next candidates.

In early-stage clinical trials, at least four other vaccines produced neutralizing antibody levels in non-elderly adults that were in line with those of BNT162b2 from Pfizer Inc. (NYSE:PFE) and BioNTech SE (NASDAQ:BNTX), and for the most part, the vaccines’ titers fell less with age than BNT162b2...