1110 ECP CatalYm
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Emerging Company Profile

CatalYm: opening up tumors to immune cells

Emerging Company Profile: German start-up targets GDF15’s immunosuppressant function to enable immune cell infiltration to tumors

Berlin-based CatalYm aims to resensitize cancer cells to checkpoint inhibitors by targeting GDF15, which restores the ability of immune cells to infiltrate the tumor.

Nov 11, 2020 | 12:15 AM GMT

CatalYm is targeting a lesser known immunosuppressant function of GDF15 to resensitize cancer patients to checkpoint blockade and enhance the ability of CAR T therapies to infiltrate solid tumors.

The Munich-based biotech has raised €50 million ($58.2 million) in a series B round led by Vesalius Biocapital III

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