Cygnus Therapeutic Systems other research news

Data suggesting that drugs of up to 1,100 molecular weight can be delivered through the skin by an electric current were published in the Proceedings of the National Academy of Sciences. Results with electroporation in human cadaver skin and in rats showed that electric pulses lasting only microseconds or milliseconds could deliver charged molecules across skin, in amounts a thousand-fold greater than what is achievable by another transdermal technique, iontophoresis, that uses a steady charge.

In the rats, no skin damage was observed after pulsing at voltages below 150 V, while swelling was seen at higher voltages. ...