Isis Pharmaceuticals preclinical data

ISIP presented preclinical data on its antisense agent now in Phase I testing in solid tumors. In experiments in which human tumors were implanted under the skin of nude mice, the agent blocked growth of the tumors as a single agent and in combination with traditional chemotherapeutics. As presented at the International Roundtable on Nucleosides, Nucleotides and Their Biological Applications in La Jolla, Calif., some combinations gave complete cures of the animals. ...