Alpha-Beta preclinical data

ABTI presented evidence for a previously unknown receptor on neutrophils and monocytes that would explain the actions of its Betafectin compound. The Betafectin carbohydrate appears to bind to a receptor that stimulates signal transduction by induction of NF-kappa B and NF-IL6, company scientists and university collaborators reported at the meeting of the Federation of American Societies for Experimental Biology in New Orleans.

Betafectin causes dose-dependent induction of the proteins. Its effect is to prime neutrophils and monocytes to kill bacteria with reactive oxygen molecules. Inflammatory cytokines, by contrast, are not induced by the agent. ...