Saquinavir HIV protease inhibitor data

A six-month trial of the Nutley, N.J., company's protease inhibitor lowered blood levels of HIV and increased CD4 counts in almost all of 40 HIV-positive, asymptomatic participants taking a high dose.

Half of trial enrollees took the agent at twice the previously tested dose, and the other half took quadruple the dose, 7200 mg/day. ...