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University of Colorado School of Medicine other research news

October 23, 1995 7:00 AM UTC

The molecular basis for the ability of testis tissue to escape graft rejection has been identified as the Fas ligand (FasL), a cell surface molecule that interacts with its receptor (Fas) in regulating immune responses.

Resting T cells express low levels of Fas, but levels rise after antigen engagement, and eventually cause apoptosis of T cells in order to turn off immune responses. ...