Zynaxis preclinical data

ZNXS (Malvern, Penn.) reported in vitro results showing a 20-fold improvement in cellular uptake of oligos using Zyn-Linkers compared to Lipofectin, a commercially available lipid vehicle.

As presented at the Keystone Symposium on Drug Delivery, a conjugate of the 18-mer anti- c-myc oligonucleotide labeled with a fluorescent marker showed increased uptake in smooth muscle cells of rabbit aorta. ...