Bristol-Myers Squibb, University of Minnesota other research news

Researchers reported in Science that 100 percent of mice treated with less than one-tenth of the maximally tolerated dose of the immunoconjugate survived implants of human leukemia cells that are otherwise fatal.

The CD19 receptor is specific to B cells and is expressed on the surface of leukemia cells in 85 percent of patients with acute lymphoblastic leukemia. The receptor is linked with the tyrosine kinase enzyme that serves as a signal inside cells to regulate cell division. Genistein is a naturally occurring inhibitor of the enzyme present in soybeans. ...