Regeneron other research news

REGN (Tarrytown, N.Y.) and university collaborators have identified several protein factors that act at a family of receptors called EPH-related receptors, whose ligands were previously unidentified, and that are thought to play a role as mediators of neuronal processes.

The scientists cloned the factors, called EFLs (EPH-family ligands), based on their ability to bind to EPH-related receptor tyrosine kinases. Other receptor tyrosine kinases bind such growth factors as insulin and nerve growth factor. Many of these receptors with unidentified ligands are expressed in the central nervous system. ...