Zyn-Linker data

The Malvern, Penn., company presented results in a rabbit model showing that Zyn-Lynker conjugates bearing rhenium-186 and yttrium-90 bound rapidly to synovial (joint-lining) cells and remained localized in the animals' knee joints.

Based on the results presented at the Mid-Eastern Chapter Society of Nuclear Medicine Meeting, the company does not expect the Zyn-Linker therapy to expose other tissues to unacceptable levels of radiation. ZNXS said the agent will cause no more, and in some cases less, radiation exposure outside the joint than available diagnostic radioactive materials. ...