Remune data

IMNR and other researchers published results of a long-term follow-up study started in 1987 in the Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. The trial in 25 HIV-positive patients with a median CD4 count of 375 included 23 who were symptomatic and 2 who were aymptomatic when they enrolled. Over a three-year period, patients received a median of 8 open-label inoculations of 100 µg of Remune in incomplete Freund's adjuvant. Patients were followed for six years.

Patients who developed an HIV-specific immune response, as demonstrated by a delayed-type hypersensitivity response (positive skin test to HIV), did better than those who didn't. Of the 12 patients who became skin test positive, only one developed an opportunistic infection, about five years after the trial began, and subsequently died. One skin test positive patient also developed Kaposi's sarcoma. ...