ARTICLE | Clinical News

Protein predictive of breast cancer survival

April 20, 2006 1:07 AM UTC

Researchers from the Rene Huguenin Cancer Centre published in Cancer Letters that survival rates were greater in certain types of breast cancer patients who had detectable levels of soluble lymphocyte activation gene-3 (sLAG-3) protein at diagnosis compared with patients with undetectable sLAG-3 levels. The researchers studied serum samples from 246 patients who were newly diagnosed in 1994. They found that 10 years later, patients with estrogen or progesterone receptor positive tumor cells who had detectable levels of sLAG-3 ended up with improved disease-free and overall survival rates versus those with undetectable levels. ...