Non-human primate data shed light on correlates of protection and duration of immunity to COVID-19 vaccines

Two more COVID vaccine developers have published non-human primate data suggesting efficacy, bringing the total to five. One of the new papers builds on the case for neutralizing antibodies as key correlates of protection; the other suggests immunity can last at least three months.

On Thursday, a Nature article describing Ad26.COV2.S from Johnson & Johnson (NYSE:JNJ) linked higher titers of neutralizing antibodies against SARS-CoV-2 to lower levels of the virus in the lungs of rhesus macaques, without a requirement for strong T cell responses. ...