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Tapping astrocytes to replace lost neurons in Parkinson’s

UCSD researchers utilize transdifferentiation to rebuild the lost neuronal pathways in Parkinson’s disease

In the latest example of a regenerative medicine approach that involves transforming one cell type in the body into another, a University of California San Diego team has shown it can replace lost dopamine neurons in a mouse model of Parkinson’s disease by reprogramming astrocytes. The mice showed substantial motor improvements.


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