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Regeneron enhances checkpoint therapy with CD28 bispecifics; plus NIH funds Alzheimer’s brain mapping, Genentech and more

BioCentury’s roundup of preclinical news

Regeneron combines CD28 bispecifics with PD-1 mAb
In its latest paper covering anti-CD28 bispecific antibodies, Regeneron Pharmaceuticals Inc. (NASDAQ:REGN) showed in Science Translational Medicine that the bispecifics could boost anti-PD-1 efficacy. Bispecifics against CD28 and PSMA, or CD28 and EGFR, synergized with an anti-PD-1 mAb to activate T cells

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