A peptide fusion blocker for multiple coronaviruses, the cryo-EM structure of SARS-CoV-2 main protease, plus Locus, Excision and Harvard-Dana-Farber

BioCentury’s roundup of preclinical news

Fudan University develops pan-coronavirus inhibitor
A team led by Fudan University researchers has developed a lipopeptide-based pan-coronavirus inhibitor of viral membrane fusion. Described in a preprint on the bioRxiv server, the lipopeptide binds the SARS-CoV-2 and MERS-CoV spike proteins outside its receptor-binding domain, and prevents the spike

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