BioCentury
ARTICLE | Product Development

Coming competition in myasthenia gravis

Clinical data in myasthenia gravis starts to separate which mechanisms do and don’t work

February 29, 2020 12:09 AM UTC
Updated on Feb 29, 2020 at 12:20 AM UTC

A comparison of therapies that have shown promise, or failed to do so, in myasthenia gravis suggests targeting production of autoantibodies may be a less fruitful approach than blocking the effects of the autoantibodies or their recycling pathways.

Patients with the rare autoimmune disease generalized myasthenia gravis saw the first targeted therapy for the disease approved two years ago. Now, biopharmas are testing several new therapeutic mechanisms, with three different molecules slated to read out Phase III data by next year...