Neutrophil mimics block cytokines behind RA inflammation

University of California San Diego researchers engineered neutrophil-mimicking nanoparticles to serve as decoys and broadly intercept pro-inflammatory cytokines that contribute to development of rheumatoid arthritis.

During RA development, activated neutrophils in the joints cause synovial cells to secrete chemokines that recruit more neutrophils, leading to an influx that mediates RA joint inflammation and damage...