Raising KRAS
How Wellspring, Janssen team showed potential of KRAS inhibitor for cancer
For the first time, a joint research team from Wellspring Biosciences LLC and the Janssen Research & Development unit of Johnson & Johnson (NYSE:JNJ) showed a small molecule K-Ras (KRAS) inhibitor worked in animal models of cancer. The results could pave the way for clinical development of a therapy against the target, a member of the notoriously “undruggable” Ras family of proteins.
Kevan Shokat, co-founder of drug discovery incubator Wellspring and professor at the University of California San Francisco, told BioCentury the latest study means “all signs are a go to get this into humans.”...
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