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Gut check

How double-edged bacteria could help -- or harm -- the gut’s immune system

A Nature study from New York University has shown the T cell regulator MAF determines whether the intestinal immune system of mice responds to certain bacteria with a protective Treg population or a pro-inflammatory Th17 population. This two-sided response could explain how some microbes -- dubbed “pathobionts” for their ability to induce pathogenic T cells -- contribute

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