ARTICLE | Emerging Company Profile

Going non-viral

Why Generation Bio’s ceDNA vectors could treat diseases AAVs cannot

February 3, 2018 1:36 AM UTC

Generation Bio Co. aims to take gene therapies into pediatric and other indications where adeno-associated virus vectors have not been able to go.

The company is developing preclinical gene therapies that are encoded in eukaryotic closed-ended DNA (ceDNA) vectors, which are linear, double-stranded DNA molecules whose ends have been closed via covalent linkages...

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Generation Bio Co.