ARTICLE | Preclinical News

New inflammasome target for early intervention in AD

December 22, 2017 12:01 AM UTC

A paper published in Nature suggests inhibiting the inflammasome protein PYD and CARD domain containing (PYCARD; ASC) may prevent beta amyloid deposition in Alzheimer's disease, offering an earlier intervention than targeting established amyloid plaques.

The study was led by University of Bonn professors Eicke Latz and Michael Heneka. Latz is scientific co-founder of inflammation company IFM Therapeutics LLC (Boston, Mass.) and Heneka is on IFM's clinical advisory board...