Building up nerve

AxoSim Technologies LLC has developed a 3-D human nerve-on-a-chip platform to recapitulate the in vivo organization of nerve bundles with greater fidelity to human systems than competitor models. The service provider is positioning its system both for preclinical neurotoxicity testing and modeling of diseases that affect axon tracts.

According to CEO Lowry Curley, the platform should be particularly useful for modeling peripheral neuropathy, demyelinating diseases like multiple sclerosis and certain neurodegenerative disorders, such as amyotrophic lateral sclerosis...