ARTICLE | Product R&D

Wave’s purity progress

Wave reveals how it makes its stereopure oligos

September 28, 2017 9:00 PM UTC

Wave Life Sciences Ltd.’s latest data releases provide the fullest view to date into how the company synthesizes its stereopure oligos and the benefits that can be derived from the chemistry. But whether the technology represents a revolution or an evolution in the space remains to be seen.

Small molecule companies have long understood the value of stereopure compounds and devised methods to make or isolate them. However, Wave founder and original CEO Gregory Verdine told BioCentury that oligo companies had simply ignored stereochemistry before Wave launched in 2012. ...