Bugs on the clock

How the obesity, circadian rhythms and the microbiome are connected

Researchers from University of Texas Southwestern Medical Center have discovered a link between the gut microbiome and the circadian mechanisms that regulate body fat storage. Their findings implicate nuclear factor interleukin-3 regulated (NFIL3) as a new target in obesity and suggest the transcription factor's expression could be reined in with a microbiome-based therapy.

Epithelial cells in the gut absorb fatty acids from food and export them into

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