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Canakinumab reduces lung cancer mortality, headed for Phase III

Novartis AG (NYSE:NVS; SIX:NOVN) said canakinumab (ACZ885) significantly reduced lung cancer incidence and associated mortality vs. placebo in the Phase III CANTOS cardiovascular outcomes trial in patients with a prior heart attack and inflammatory atherosclerosis. Spokesperson Eric Althoff told BioCentury that Novartis plans to start Phase III trials of the mAb against IL-1

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