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Better glioma mouse models

CRISPR-edited mouse models for glioma

To accelerate the generation of glioma mouse models and find new oncogenic gene fusions, researchers from Memorial Sloan Kettering Cancer Center (MSKCC) have used CRISPR-based gene editing to produce mice in a method designed to be easily scalable and relevant for preclinical testing.

The goal was to create a system that could pick out oncogenic drivers from the thousands of

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