BioCentury
ARTICLE | Strategy

Henri: N of 1

How the late Genzyme CEO Henri Termeer created the Orphan drug industry

May 20, 2017 12:05 AM UTC

Gaucher’s disease had swollen Brian Berman’s spleen to the size of a basketball and physicians at NIH told the three-year-old’s parents that it had to be removed.

It was 1984, there was no effective treatment for the rare genetic disorder, and the surgery would do nothing to change a prognosis that was grim and certain: years of deformity and unremitting pain relieved only by death...

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Genzyme Corp.