ARTICLE | Tools & Techniques
The phenomics phenomenon
Why phenotypic screens are making a comeback
March 23, 2017 11:51 PM UTC
Having been upstaged by the dawning of genomics over 20 years ago, phenotypic screening is making a comeback as improvements in disease models, advances in microscopy and the rise of machine learning are making it easier to measure disease-relevant phenotypes and track down the targets responsible.
The dominant paradigm in drug discovery centers on identifying a target, often through genetic screening, and then working out how to drug it...