High-altitude hypoxia

Researchers have uncovered a pathway in human blood that helps cells cope with low oxygen levels at high altitudes, and have shown in mice that a target in pathway -- solute carrier family 29 nucleoside transporter member 1 (SLC29A1; ENT1) -- may be useful for treating hypoxia.

The group, led by researchers at the University of Texas Health Science Center, started with data from the Human AltitudeOmics Study -- in which 21 healthy volunteers hiked up and down Bolivia’s Mount Chacaltaya multiple times to help characterize the biology behind successful acclimatization and why the process happens faster after a second climb. ...