ARTICLE | Tools & Techniques

Eggs over easy

How skin cells can be transformed into oocytes in a dish

November 22, 2016 3:02 AM UTC

A Japanese group has brought the field of reproductive medicine one stride closer to the elusive goal of artificially generating oocytes in vitro, with a study detailing a suite of steps to convert a mouse skin cell into a mature oocyte ready for IVF. While the process yielded live, fertile pups, the group thinks the host of differences between mice and humans might slow translation of the results to the clinic.

Nevertheless, the researchers believe the mechanistic insights that can be gleaned using the process will prove important for creating new fertility treatments...