ARTICLE | Distillery Therapeutics

Therapeutics: Oxysterol binding protein 2 (OSBP2; ORP4)

October 13, 2016 7:00 AM UTC

Cell culture and mouse studies suggest inhibiting OSBP2 could help treat T cell ALL. In a human T cell ALL cell line, shRNA targeting OSBP2 decreased survival compared with scrambled shRNA. In a xenog...