ARTICLE | Distillery Therapeutics

Therapeutics: Dicer 1 ribonuclease type III (DICER1); programmed cell death 1 (PD-1; PDCD1; CD279); CD40

June 30, 2016 7:00 AM UTC

Mouse studies suggest macrophage-specific inhibition of DICER1 could help treat cancer. In an orthotopic mouse model of breast cancer and a mouse model of lung cancer, DICER1 knockout in macrophages d...