Concentrating on HTS

When James Inglese and Douglas Auld were getting their screening lab set up at NIH, they encountered more red tape than expected. As a result, the researchers found themselves flush with a scarce resource - free time. The time was not spent idly, as they used it to theorize a new screening system that would overcome many limitations of current high throughput technology. Recently, they and colleagues published the system in the Proceedings of the National Academy of Sciences.

"The bureaucracy in putting our lab together dragged along," said Inglese, the lead author. "That gave us time to think in depth" about the optimal characteristics of a screening system...