ARTICLE | Emerging Company Profile

Airway: Pulmonary D-fense

Airway adding rhSP-D to other surfactants to prevent lung injury in newborns

March 12, 2012 7:00 AM UTC

Products containing surfactant proteins B and C have reduced mortality caused by respiratory distress syndrome in premature newborns, but chronic bronchopulmonary dysplasia caused by ventilation remains a problem. Airway Therapeutics LLC has shown adding surfactant protein D to marketed products can further reduce lung inflammation in animals, and is in talks with marketers to co-develop a combination product.

Pulmonary surfactants are a family of collectin proteins thought to ensure proper lung function by maintaining structural integrity during inhalation and exhalation...