Haplogen: Mining for host factors
Haplogen screening haploid cells for new host-factor targets to block infections
Haplogen GmbH is screening haploid human cells to identify new host factors required for bacterial or viral infection, which it hopes will lead to the development of anti-infectives with less potential for resistance.
Haplogen was founded to commercialize a screening system developed in the lab of one of the company's scientific founders, Thijn Brummelkamp, at the Whitehead Institute for Biomedical Research.
In work published in Science in 2009, Brummelkamp and his team provided the first proof of concept that