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Eureka: Finding foreign signatures

Eureka aims to identify new links between microorganisms, disease

September 13, 2010 7:00 AM UTC

Eureka Genomics Corp. is using its ability to detect and identify DNA from an unknown source to discover associations between microorganisms and disease. The ultimate goal is to develop molecular diagnostics that detect microorganisms associated with chronic diseases like cancer, cardiovascular and neurological disorders. Much as discovery of the link between HPV and cervical cancer revolutionized the treatment paradigm for that disease, Eureka hopes its work will enable earlier detection and intervention, and ultimately new vaccines and treatments.

Most sequence analysis tools for identifying non-host DNA require a researcher to hypothesize which pathogen or microorganism could be associated with disease. The known DNA sequences of those organisms are then compared with DNA sequences from human tissue or blood samples...