ARTICLE | Tools & Techniques

Bigger is better

X-Chem's DNA-encoded technology to identify high-quality lead candidates

February 24, 2014 8:00 AM UTC

X-Chem Inc. has developed a screening platform and library of DNA-encoded small molecules that enable the identification of high-quality lead candidates against difficult targets. So far, the platform has yielded a handful of discovery deals, including two that have resulted in licenses to small molecule candidates.

Most recently, on Feb. 13, X-Chem announced that Bayer AG licensed an undisclosed number of compounds discovered under a 2012 deal. The compounds inhibit an undisclosed epigenetic target...