ARTICLE | Tools & Techniques

Pathogen sensors

August 15, 2005 7:00 AM UTC

The Toll Collectors

Toll-like receptors are transmembrane proteins that were discovered nine years ago in Drosophila when scientists noted that knockout flies lacking TLR genes lost their immunity to fungal infections. In humans, 12 TLRs have been reported, though the twelfth has not been described. ...