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Sagres: Sifting wheat from chaff

One of the big issues in target discovery today is the fact that hundreds of genes may be up-regulated in any given disease state. Such is the obstacle in comparing cancerous and healthy tissue. To solve that problem, Sagres Discovery Inc. has taken a 20-year old technology - insertional mutagenesis using a retrovirus to identify causative cancer genes - and made it high throughput.

Sagres' technology has its origins at the University of California at Davis, where

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