Do-it-yourself genotyping

Recent initiatives to include the general public in genotyping research have increased awareness of the role of individual genetic variation in determining response to drug treatment. Taking a cue from direct-to-consumer pharmaceutical advertising, pharmacogenomics companies now are taking the next step, giving patients the possibility of directing their own treatment options through genetic tests marketed directly to the public.

In a few weeks, for example, PPGx Inc. will launch its internet-based direct-to-consumer genotyping test for five alleles of the 2D6 cytochrome P450 gene. The gene has a primary role in regulating the

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