Inpharmatica: 3-D bioinformatics
Like many bioinformatics companies, Inpharmatica uses public domain databases to draw comparisons with clients' proprietary sequences. However, instead of simply comparing unknown client sequences with annotated public sequences to predict functionality, Inpharmatica also compares 3-D structure with 3-D structure. This can group proteins by their structure and allows the detection of genes with different sequences but potentially the same function.
The company's approach is based on the