GlycoDesign: On familiar ground

Proteins are the rage as targets for therapeutic development, but other molecules play pivotal roles in functions such as intercellular signaling. Carbohydrates, for example, participate in signal recognition on cell surfaces as part of glycoprotein receptors. GlycoDesign Inc. has assembled a platform for discovery of small molecule therapeutics that interfere with enzymes responsible for making cell-surface carbohydrates. Such therapeutics would modify the behavior and sensitivity of glycoprotein receptors.

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